Epithelial changes produced by irritation

Electrophysiologic Changes Produced by Intravenous Alcohol

The effect of alcohol (.1 mg/kg) on the sinus node and atrioventricular node was studied in 9 mongrel dogs. The sinus node function was evaluated by the sinus node recovery time and the atrioventricular node by the highest atrial pacing rate at which Wenckebach periodicity was developed. The effect was studied for 45 minutes. Three groups were identified: Group I, Low Concentration of Alcohol (...

Spatial summation of chemical irritation and itch produced by topical application of capsaicin.

The effect of increasing the total area of stimulation on the sensations of irritation produced by topical application of capsaicin was studied in two experiments. In the first experiment, stimulus area was varied by changing the size of filter paper disks on which capsaicin was delivered to the skin of the forearm. Subjects rated the intensity and quality of the cutaneous sensations over a 15-...

Paracrine glucocorticoid activity produced by mouse thymic epithelial cells.

Previous data have suggested that glucocorticoids (GCs) are involved in the differentiation of thymocytes into mature T cells. In this report we demonstrate that the mouse thymic epithelial cells (TEC) express the cytochrome P450 hydroxylases Cyp11A1, Cyp21, and Cyp11B1. These enzymes, in combination with 3beta-hydroxysteroid dehydrogenase (3betaHSD), convert cholesterol into corticosterone, th...

Sequential cellular changes produced by african horse sickness virus in monkey kidney cells

Changes in Syllable and Boundary Strengths Due to Irritation

This study examines prosodic characteristics of speech in dialogue exchanges. Subjects were asked to repeat the same correction of one digit in a three-digit sequence consisting of ‘five’ or ‘nine,’ followed by ‘Pine Street.’ Articulatory and acoustic signals were obtained on four speakers of General American English at the University of Wisconsin x-ray microbeam facility. These data are analyz...